
Southeastern Indiana Vacations from $353
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Your Southeastern Indiana Vacation
Head off on your next big adventure with a Southeastern Indiana vacation package, and leave knowing all the details are organized. And with the ability to customize your getaway, you know it'll be one to remember. Your trip to Southeastern Indiana wouldn't be complete without getting to some of its most well-known cities, starting with Louisville. A couple of the top attractions here include KFC Yum Center and Kentucky Kingdom. Radcliff should also be on the itineraries of all Southeastern Indiana travelers. Visitors to this exciting city love Freeman Lake Park and General George Patton Museum. Whether you're planning to travel for a few days or a few weeks, Expedia are here to help you tailor-make your next dream Southeastern Indiana vacation.
The Latest Southeastern Indiana vacation packages

Hollywood Casino & Hotel
Reviewed on Jan 7, 2026


Hilton Garden Inn Louisville Mall of St. Matthews
Reviewed on Jan 7, 2026


Hotel Covington Cincinnati Riverfront
Reviewed on Jan 3, 2026
Where to stay in Southeastern Indiana

West Main Historic District
Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.
Discover the most popular places to visit in Southeastern Indiana

Louisville Slugger Museum
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

Whiskey Row
Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Muhammad Ali Center
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North
The customer service was excellent she was very understanding of what was going on in my family and I felt like she made it very manageable for me. Thanks for all you done!!!
Reviewed on Jan 6, 2026

Hampton Inn New Albany Louisville West
Didn’t get to get breakfast I slept straight through it. Rooms very clean staff was great
Reviewed on Jan 1, 2026

TownePlace Suites by Marriott Louisville North
Clean room, staff at check in and breakfast
Reviewed on Dec 23, 2025
Find the Best Southeastern Indiana Vacation Packages
Southeastern Indiana Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | O'Hare Intl. Airport (ORD) |




















